Completed Projects

Projects completed by the Biomarkers Consortium include:

Project Name/Committee Objective completion Date
Sarcopenia Consensus Summit [MDSC] Generate the first consensus evidence-based definition of sarcopenia (age-related decrease in skeletal muscle mass) to provide specific guidelines for clinical diagnosis and enable future regulatory decisions regarding treatments of this currently unrecognized condition July 2013 - seven manuscripts submitted for publication in JGMS
Carotid MRI Reproducibility Project [MDSC] Establish a standardized carotid MRI protocol and determine the impact of site/platform on reproducibility of the measurements July 2013 - two manuscripts submitted for publication
Alzheimer’s Disease (AD) Targeted Plasma Proteomics Project [NSC] Qualify a multiplexed panel of known AD plasma-based biomarkers using plasma samples from the Alzheimer’s Disease Neuroimaging Initiative (ADNI) July 2012 - Results published in Arch Neurol. 2012 Oct;69(10):1310-7
- AAIC poster 2012
PET Radioligand Project [NSC] Develop improved, more sensitive radioligands with higher binding to the peripheral benzodiazepine receptor Dec 2012 - Results published in Alzheimers Dement. 2012 February;8(10): S1–68 and Brain. 2013 Jul;136(Pt 7):2228-38
- AAIC poster and oral presentation 2013
Adiponectin Project [MDSC] Determine whether adiponectin has utility as a predictive biomarker of glycemic control June 2008 -Results and lessons learned published in Clin Pharmacol Ther. 2009 Dec;86(6):619-25 and Clin Pharmacol Ther. 2010 May; 87(5): 539-42
- Posters presented at the ASCPT and ADA 2009